Area Of Interest Research Articles

Review on Pyrazole Hybrids as Anti-microbial Agents

Abstract: A five-membered heteroaromatic ring with two nitrogen atoms, pyrazole, is of immense significance. Pyrazole and its derivatives are well-known nitrogen-containing heterocyclic compounds that are significant in medicinal chemistry and have a variety of biological properties, according to a thorough analysis of this class of heterocyclic lead. This article summarises some biologically active, potent pyrazole hybrids and their structure-activity relationship for antimicrobial activity published by various researchers across the world. It is divided into two sections. The first part summarizes recent developments in pyrazole derivatives for various biological activities, such as anti-Alzheimer’s, antioxidant, anticancer, anti-inflammatory, and antiviral, while the second section focuses on a detailed substitution analysis of pyrazole with its hybrid, which is the structure-activity relationship needed for antimicrobial activity. The presence of pharmacological potential of pyrazole moiety has been demonstrated by the role of a nucleus in pharmacological agents from different therapeutic groups, such as the potent anti-inflammatory agent celecoxib, anti-obesity drug rimonabant, analgesic diphenamizole, H2-receptor agonist betazole, and antidepressant agent fezolamide. The design of new pyrazole derivatives has become an interesting research area due to their versatile nature and biological significance. Moreover, it has been observed that pyrazole in combination with another moiety has a strong potent antimicrobial effect.

Incorporating Mental Health Literacy Into the Sport Management Curriculum

Mental health is an emerging area of interest in sport, but there is a paucity of educational initiatives in sport management curricula to train the next generation of sport managers to address the mental health needs of athletes, a type of knowledge that the mental health literature operationalizes as mental health literacy. One goal of accrediting bodies such as the Commission on Sport Management Accreditation is for excellence in sport management education; thus, due to the changing landscape of sport, sport management curricula should incorporate mental health literacy competencies. This educational research review provides justification for the inclusion of mental health literacy competencies in sport management curricula and accreditation standards, as well as pedagogical strategies for implementation.

Energy-Efficient Device-to-Device Communications for Green Internet of Things Using Unmanned Aerial Vehicle-Mounted Intelligent Reflecting Surface

The Internet of Things (IoT) serves as a crucial element in interconnecting diverse devices within the realm of smart technology. However, the energy consumption of IoT technology has become a notable challenge and an area of interest for researchers. With the aim of achieving an IoT with low power consumption, green IoT has been introduced. The use of unmanned aerial vehicles (UAVs) represents a highly innovative approach for creating a sustainable green IoT network. UAVs offer advantages in terms of flexibility, mobility, and cost. Moreover, device-to-device (D2D) communication is essential in emergency communications, due to its ability to support direct communication between devices. The intelligent reflecting surface (IRS) is also a hopeful technology which reconstructs the radio propagation environment and provides a possible solution to reduce co-channel interference resulting from spectrum sharing for D2D communications. The investigation in this paper hence focuses on energy-efficient UAV-IRS-assisted D2D communications for green IoT. In particular, a problem of optimization aimed at maximizing the system’s average energy efficiency (EE) is formulated, firstly, by simultaneously optimizing the power coefficients of all D2D transmitters, the UAV’s trajectory, and the base station (BS)’s active beamforming, along with the IRS’s phase shifts. Second, to address the problem, we develop a multi-agent twin delayed deep deterministic policy gradient (MATD3)-based scheme to find a near-optimal solution, where D2D transmitters, the BS, and the UAV cooperatively learn to improve EE and suppress the interference. To conclude, numerical simulations are conducted to assess the availability of the proposed scheme, and the simulation results demonstrate that the proposed scheme surpasses the baseline approaches in both convergence speed and EE performance.

Tools to measure the burden on informal caregivers of cancer patients: A literature review.

(1) To describe existing tools to assess the burden of informal caregivers of people with cancer, (2) to describe how these tools have been validated and (3) to describe the areas of interest of existing assessment tool entries. The caregiver burden of informal caregivers of people with cancer greatly affects their lives. There is a wide variety of relevant assessment tools available, but there are no studies to help researchers to select tools. A search was conducted using the keywords 'cancer', 'caregiver', 'burden' and 'scale' in Medline (PubMed), CINAHL and EMBASE to include articles that developed or applied tools to assess the burden on informal caregivers of cancer patients. Once eligible tools were identified, we searched their 'primary reference' studies. If the original scale was assessed in a population other than informal caregivers of cancer patients, we again searched for psychometric measures in the population of caregivers of cancer patients. This study retrieved 938 articles on developing or applying the informal caregiver burden instrument for cancer patients, including 42 scales. Internal consistency of the original scales ranged from 0.53 to 0.96. Nineteen scales initially developed to assess caregiver burden for patients with dementia, stroke and other disorders were later used for caregivers of cancer patients, eight of which have not yet been validated. Reclassifying all scale domains of concern revealed that scale assessments focused more on caregivers' physical health, emotional state and caregiving tasks. This review identifies many scales for assessing informal caregiver burden in cancer patients and gives scales recommended. However, a portion still needs to be validated. The development of a new scale proposes to be based on a theoretical framework and to consider dimensions for assessing support resources. What problem did the study address?: This paper collates assessment tools on the burden of informal carers of people with cancer. It also provides information on the applicable population, reliability and validity. What were the main findings?: 41 scales could be considered for use, eight of which have not been validated. The scales focus more on assessing caregivers' physical health, emotional state and caregiving tasks, and less on the dimension of support resources. Where and on whom will the research have an impact?: There are implications for informal carers of cancer patients in hospitals or in the community, as well as for relevant researchers. Retrieved with reference to systematic evaluation. No patient or public contribution.

Lakeshore areas of conservation interest: Characteristics of nursery areas of the threatened lake‐dwelling grayling, Thymallus thymallus

AbstractResearch‐based knowledge is essential for effective conservation and restoration of threatened aquatic species and habitats. Here, our aim was to gather this knowledge on the lake‐dwelling grayling (Thymallus thymallus), typically a riverine fish. Such atypical populations are particularly vulnerable to anthropogenic impacts, including fishing pressure, climate change, eutrophication and waterway construction, some of which affect especially the early life stages. However, there is little information available to guide management and conservation of grayling in lakes. Accordingly, we assessed characteristics of the nursery areas in the threatened grayling population of Lake Puruvesi (eastern Finland). In particular, we used beach seines in two consecutive years to sample lakeshore sites (including islands) that were a priori presumed suitable for grayling. We assessed the occurrence of grayling fry (larvae and post‐larvae <40 mm in length) regarding depth, year, the site's exposure (fetch), bottom shear stress, substrate coarseness and shoreline's north–south orientation. Overall, we found grayling fry in low numbers at every fourth site, with the sites’ exposure and dominant substrate coarseness being most relevant variables. In particular, more exposed sites (i.e. with higher fetch values) and fine‐grained substrates dominated by sand or gravel had more grayling fry. Average depth, bottom shear stress or shoreline orientation along the north–south axis did not have a significant effect. Together, the results suggest that the most important nursery areas for lake‐dwelling grayling are lakeshore zones that are barren and exposed. Hence, the sites share characteristics with those used for reproduction by the more common riverine grayling. We hope that these findings will facilitate lake‐dwelling grayling's management and conservation efforts.

Unveiling the neuroprotective potential of chrysin on the pre-frontal cortex of adult male Wistar rats

Objectives Excessive free radicals in the human body predispose cells within the various systems to an imbalance and accumulation of oxygen-reactive species, known as oxidative stress. The central nervous system is not spared when it comes to these cell and tissue damages. Oxidative stress on the central nervous system may be responsible for anxiety, spatial memory impairment, neuronal cell depletion, and vacuole-tissue degeneration resulting from neurotoxicity. The use of chemotherapeutic agents such as doxorubicin has been implicated in the build-up of this imbalance between oxygen-reactive species and antioxidants. Therefore, it has become an area of research interest to seek antioxidant supplements that may offer neuroprotective effects. This study is aimed to evaluate the protective potential of chrysin on the pre-frontal cortex of male Wistar rats with doxorubicin-induced cognitive impairment. Material and Methods Thirty-five adult Wistar rats (180–200 g) were grouped into seven (1–7; n = 5). Group 1, the normal control, received normal saline treatment only throughout the study. Group 2 was administered with doxorubicin only for 21 days by intraperitoneal injection. Groups 3 and 4 were administered with chrysin in low and high doses for 21 days orally. Groups 5, 6 and 7 were exposed to doxorubicin and chrysin for 21 days intra-peritoneally and orally with low, medium and high doses, respectively. Results Anti-oxidative biomarkers analysed in Group 2 (doxorubicin-only) demonstrated a significant difference when compared to other groups. This corresponded to significant elevations in apoptotic indicators, inflammatory markers and histological lesions, which were indicative of cognitive impairment. 5, 7-dihydroxyflavone (chrysin) significantly mitigated and also reversed cognitive impairment caused by doxorubicin. Conclusion The data showed that chrysin protected against doxorubicin-induced cognitive impairment. This effect is probably made possible by suppressing oxidative stress, inflammation and apoptosis.

Insect immunity - adaptive mechanisms and survival strategies

Host-pathogen interactions play an important role in understanding the dynamics of the insect immune system. The analysis of environmental modulators, both biotic and abiotic, directs our attention to the impact of the surroundings on the effectiveness of immunological responses. This knowledge is essential for the comprehensive understanding of insect’s immune reaction after infection with a pathogen. This article discusses the role of the immune system in insect, with a special emphasis on greater wax moth Galleria mellonella and highlights its adaptive capabilities. The processes are not only extremely interesting area of scientific research but also indicate potential practical applications in the context of plan protection, pest population control and medicine.

The New Neighborhood Watch: An Exploratory Study of the Nextdoor App and Crime Narratives

Community members use the Nextdoor App to prevent crime and circulate information when suspicious activity or criminal misconduct is afoot. The Nextdoor App operates like other popular social media platforms, but unlike Facebook and Twitter, it connects citizens based on geography instead of areas of interest. One unique aspect of the app is posting events and perceptions of suspicious behavior and criminal acts. User posts can provide narratives on feelings, incidents, and perceptions of crime in designated neighborhoods. This exploratory study focuses on how community members in an urban Colorado area use the app as a high-tech Neighborhood Watch. A qualitative research approach with a thematic analysis is implemented to examine neighbors’ perceptions of crime events and community safety. The findings depict that citizens engaged in Nextdoor communications are frustrated with petty community incivilities, property crimes, and law enforcement actions. In addition, the results show that lessons in being a capable guardian, possible increases in fear levels, and surveillance activities are important aspects of understanding social media and crime.

The stealth rise of control: Forgotten trust in contemporary professionalism

Professionalism has long been a term understood to distinguish social strata, commonly highlighting those trusted to employ expert knowledge for the benefit of society. Professionalism however is evolving; this position article contributes to the subject in drawing together different threads of literature beyond empirical studies to extend the discussion on professionalism, shedding a light on an area of interest. Specifically, it is argued that professionalism is threatened by the shift of the loci of control from the traditional, occupational professional positions to what is now contemporary professionalism. To facilitate such a transition, trust, a long-time fundamental component of traditional professionalism, is being readily and overtly substituted by control, wielded in and by modern organisations for the primary benefit of that organisation. The first part of the article explicates an understanding of professionalism and trust. The following section then introduces the relationship between both traditional and contemporary professionalism with trust. The third part moves to discuss the rise of differing types of control, arguing that trust has been forced to take a minor role in contemporary notions of professionalism in organisational practice, leading to the term being utilised to induce the required behaviours within those organisations. The article concludes with direction on both potential implications and applications of the theoretical points raised through the discussion.

Bilateral treaty networks: assessing cooperative spillover in defense and investment

Abstract The potential for mutual influence or “spillover” between economic and security cooperation is a long-standing area of interest for policymakers and scholars alike. This paper examines how network dynamics affect spillover. We focus on two prominent types of formal bilateral cooperation—defense cooperation agreements (DCAs) and bilateral investment treaties (BITs)—both of which have proliferated dramatically in the post-Cold War international system. We argue that existing theoretical and empirical approaches to economic-security spillover focus too strictly on influences at the bilateral level. As with other forms of international cooperation, BITs and DCAs comprise larger international networks. Governments develop portfolios of BITs or DCAs with distinct structural goals in mind, and they implement specific strategies in pursuing those goals. With BITs, governments follow a network-hierarchy strategy that allows them to influence treaty design and protect their firms. In DCAs, governments instead favor a network-community strategy focused on pooling collective security goods among groups of like-minded collaborators. When these network strategies complement one another, they promote cooperative economic-security spillover. When they conflict, however, they inhibit spillover, such that cooperation in economic or security issues discourages cooperation in the opposing issue area.

TENet: A Texture-Enhanced Network for Intertidal Sediment and Habitat Classification in Multiband PolSAR Images

This paper proposes a texture-enhanced network (TENet) for intertidal sediment and habitat classification using multiband multipolarization synthetic aperture radar (SAR) images. The architecture introduces the texture enhancement module (TEM) into the UNet framework to explicitly learn global texture information from SAR images. The study sites are chosen from the northern part of the intertidal zones in the German Wadden Sea. Results show that the presented TENet model is able to detail the intertidal surface types, including land, seagrass, bivalves, bright sands/beach, water, sediments, and thin coverage of vegetation or bivalves. To further assess its performance, we quantitatively compared our results from the TENet model with different instance segmentation models for the same areas of interest. The TENet model gives finer classification accuracies and shows great potential in providing more precise locations.

MRNA expression profiling of leptin and adiponectin and its receptors in colorectal carcinoma – Biomarker development

BackgroundMetastatic colorectal carcinoma (CRC) is one of the leading causes of mortality of colorectal CRC. Very few prognostic markers and factors affecting progression are studied between metastatic CRC and early CRC. Adipokines are speculated to be associated with this area of interest. In the current study leptin, leptin receptor (Ob-R), adiponectin, adiponectin R1, and adiponectin R2 expression were measured at gene levels to determine a possible association between adipokines and early/metastatic cancer to ultimately identifying a definitive diagnostic marker. Materials and methodsTissue samples were obtained from 62 patients with radical specimens of CRC. Genes expression was determined by Quantitative Reverse-Transcription Polymerase Chain Reaction (qRT-PCR). The association between the clinicopathological parameters and gene expression levels were analyzed by statistical analysis. ResultsOverexpression of leptin mRNA is observed in small tumors (size< 5 cms) (P<0.05).b. Leptin receptor were overexpressed in advanced tumors (1.013 ± 0.152) than early tumors (0.453 ± 0.131). c.Adiponectin expression was higher in early tumors (1.535 ± 0.406) than in advanced tumors (0.48 ± 0.148). d. Distant organ metastasis shows under-expression of adipoR1. e.Overexpression of adipoR2 is seen in small (size<5 cms) (P<0.05) tumors. ConclusionLEPR is better indicator of advancement of tumor than Leptin. ADIPOR1 is a better indicator in advanced CRC than ADIPOR2 and ADIPOQ.

The Rise of Data and ai in Parliamentary Proceedings – The Norwegian Parliament, Stortinget

Abstract In 2019 the administration of the Norwegian Parliament designed and adopted a strategic goal for digitization: The Parliament shall exchange, process, publish and preserve parliamentary information digitally and efficiently, with good quality. One outcome of this effort was the project “StorSak”. This project aims to implement an information system which handles document production and parliamentary proceedings in a coherent digital value-chain. One of the investment areas in the StorSak project is exploring the use of machine learning (ml) and artificial intelligence (ai). The project quickly singled out metadata handling as an area of interest, and the categorization of documents and proceedings using theme wording.

Multicultural Considerations for the Psychometrics of the Brief Pornography Screen.

Problematic pornography use (PPU) is a burgeoning area of clinical interest. The Brief Pornography Screen (BPS) is a new PPU measure. The BPS has not been psychometrically studied within specific race/cultural groups. We sought to broaden the PPU literature by examining the confirmatory factor analysis (CFA) fit, measurement invariance, and structural invariance of the BPS across eight identity groups. Participants came from a survey administered at three U.S. universities. In total, n = 2,475 participants were analyzed, with the following identity group breakdowns: Asian American/Pacific Islander (AAPI) male = 268, AAPI female = 303, Black male = 101, Black female = 189, Latin male = 208, Latin female = 372, White male = 432, and White female = 602. BPS CFA fit was good across all groups. Measurement invariance analyses suggested metric, but not scalar invariance across all groups. We then split participants by sex assignment, full residual invariance was evident across groups for male participants and partial residual invariance was evident for female participants. Structural invariance analyses indicated anxiety as a weak positive BPS correlate in AAPI, Latin, and White male participants (β's = 0.25-0.27), but not meaningfully related in the other groups. Pornography viewing frequency was positively correlated with BPS scores across most groups with a wide range (β's = 0.29-0.52), except for Black male participants (β = 0.15). Our results suggest that the BPS is an appropriate PPU measure across the tested identity groups. While between-group measurement is relatively accurate within sex assignment groups, correlates differed in strength, meaning different variables likely predict PPU for different groups of people.

Discovery of Latent Cannabichromene Cyclase Activity in Marine Bacterial Flavoenzymes.

Production of phytocannabinoids remains an area of active scientific interest due to the growing use of cannabis by the public and the underexplored therapeutic potential of the over 100 minor cannabinoids. While phytocannabinoids are biosynthesized by Cannabis sativa and other select plants and fungi, structural analogs and stereoisomers can only be accessed synthetically or through heterologous expression. To date, the bioproduction of cannabinoids has required eukaryotic hosts like yeast since key, native oxidative cyclization enzymes do not express well in bacterial hosts. Here, we report that two marine bacterial flavoenzymes, Clz9 and Tcz9, perform oxidative cyclization reactions on phytocannabinoid precursors to efficiently generate cannabichromene scaffolds. Furthermore, Clz9 and Tcz9 express robustly in bacteria and display significant tolerance to organic solvent and high substrate loading, thereby enabling fermentative production of cannabichromenic acid in Escherichia coli and indicating their potential for biocatalyst development.

Pictorial Health Warning and Intention to Quit Smoking in Smokers in an Urban Campus Jakarta

Background: Research on eye-tracking among active smokers shows they avoid the health warnings on cigarette packages, which still occur even without prominent imaging information. Aims: To evaluate the reactions and perceptions to pictorial health warning (PHW) labels by measuring eye-tracking devices and knowing their relationship to smoking cessation intention. Methods: The study used a cross-sectional design with measurements of PHW on cigarette packs by eye-tracker tools of type Tobii-data collection. With a non-random sampling technique, 50 respondents were from civitas academics on Campus-A UHAMKA. Samples were selected based on inclusion criteria: men, active smokers, not colorblind, and who didn't intend to stop smoking three months before the study. Results: The number also shows that most respondents already have strong intentions. The majority of respondents (64%) want to improve their health. However, 20% of those surveyed have no reason to quit smoking. That might represent the respondent's low intention to quit smoking. A bivariate test showed no significant association between respondents' attitudes toward smoking cessation intention (p-value: 0.706) and subjective norms for smoking cessation intention (p-value: 0.706). The eye-tracking results found that the different gaze plots and heatmap results on cigarette packets showing smoking-related diseases were more directed to the PHW area of interest. However, on smoking behavior images, the gaze plot and heatmap showed scattered results for PHW and cigarette brands. Conclusion: Although it has not been proven significantly related to smoking cessation intention, PHW has been the respondents' focus. We need further research on the shape and size of PHW.

Defining the Shape of the Mylohyoid Muscle: A Morphometric Imaging Study.

Implantable hypoglossal nerve stimulation (HNS) therapy is an evolving therapeutic alternative for patients with refractory obstructive sleep apnea (OSA). The muscular anatomy of this region has implications for surgical access through this zone as well as positioning and anchoring of hardware in this area. The purpose of this study was to radiologically describe the topography of the mylohyoid muscle and adjacent structures across a wide age spectrum. We retrospectively evaluated computed tomography scans of the neck in 102 patients who were imaged for reasons unrelated to the floor of mouth or submental space. Patients with prior surgery or pathology in the area of interest were excluded. Fourteen relevant muscle measurements were made on a midline sagittal image and a coronal image positioned at the midpoint between the hyoid bone and the mandible. We included 49 men and 53 women with an average age of 44 years (range 19-70). The average mylohyoid length was 42 mm; the average distance between the anterior digastric bellies was 17 mm. The average angle of the central mylohyoid was 174° in the sagittal plane and 164° in the coronal plane. Several measurements were significantly correlated with patient age, including the angle measurements and the distance between the digastric muscles. Aberrant digastric anatomy was common. The mylohyoid muscle has multiple radiologically distinct segments with predictable curvatures. An understanding of submental muscular anatomy, along with its variability between patients, may be beneficial to the development of bilateral implantable neurostimulation technology for the treatment of refractory OSA. N/A Laryngoscope, 2024.

An exploratory study of the effect of age and gender on face scanning during affect recognition in immersive virtual reality

A person with impaired emotion recognition is not able to correctly identify facial expressions represented by other individuals. The aim of the present study is to assess eyes gaze and facial emotion recognition in a healthy population using dynamic avatars in immersive virtual reality (IVR). For the first time, the viewing of each area of interest of the face in IVR is studied by gender and age. This work in healthy people is conducted to assess the future usefulness of IVR in patients with deficits in the recognition of facial expressions. Seventy-four healthy volunteers participated in the study. The materials used were a laptop computer, a game controller, and a head-mounted display. Dynamic virtual faces randomly representing the six basic emotions plus neutral expression were used as stimuli. After the virtual human represented an emotion, a response panel was displayed with the seven possible options. Besides storing the hits and misses, the software program internally divided the faces into different areas of interest (AOIs) and recorded how long participants looked at each AOI. As regards the overall accuracy of the participants’ responses, hits decreased from the youngest to the middle-aged and older adults. Also, all three groups spent the highest percentage of time looking at the eyes, but younger adults had the highest percentage. It is also noteworthy that attention to the face compared to the background decreased with age. Moreover, the hits between women and men were remarkably similar and, in fact, there were no statistically significant differences between them. In general, men paid more attention to the eyes than women, but women paid more attention to the forehead and mouth. In contrast to previous work, our study indicates that there are no differences between men and women in facial emotion recognition. Moreover, in line with previous work, the percentage of face viewing time for younger adults is higher than for older adults. However, contrary to earlier studies, older adults look more at the eyes than at the mouth.Consistent with other studies, the eyes are the AOI with the highest percentage of viewing time. For men the most viewed AOI is the eyes for all emotions in both hits and misses. Women look more at the eyes for all emotions, except for joy, fear, and anger on hits. On misses, they look more into the eyes for almost all emotions except surprise and fear.

AquaKey

Underwater Visible Light Communication (UVLC) is promising due to its relatively strong penetration capability in water and large frequency bandwidth. Visible Light Communication (VLC) is also considered a safer wireless communication paradigm as light signals can be constrained within the area of interest with obstacles such as walls, reducing the chance of potential attack. However, this intuitional security assumption is not true anymore in underwater environment. Recent research shows that the eavesdropping risk of UVLC is more severe than we thought, attributed to the divergence and scattering effects of light beams in water. In this paper, we harness the dynamic nature of underwater environments as a true random resource to extract symmetric keys for UVLC. Specifically, the proposed AquaKey system incorporates instantaneous bidirectional channel probing, computation of relative channel characteristics, and an environment-adaptive quantization algorithm. The above design addresses unique challenges caused by the dynamic underwater environment, including self-interference, high-frequency disturbance, and mismatch, ensuring the practicality and applicability of AquaKey. Additionally, AquaKey has negligible impact on communication and has no effect on the illumination function. Through extensive real-world experiments, we show that AquaKey can achieve reliable key extraction with cheap hardware, generating a 512-bit key in just 0.5-1 seconds.

Russian Student Readiness for Professional Service: from Actual to Desired

The phenomenon of service comes into our area of interest when we are talking about the uniqueness of Russia’s social structure and the markers that define it. Service can be included in everyday life through professional activities, therefore we can consider the subject, focusing on its type. The goal of the research is to determine the meaning of professional service, its place in the modern world, as well as the development of methodological guidelines guiding the training session. Achieving the goal would be impossible without relying on the methodology of the social and philosophical analysis, value, activity, and psychological approaches.The following problems that structure the presentation of the material have been solved. 1. The origins of the idea of service and the ways of its development in Russian society are revealed. Retrospectively the transformation of the ministry is considered from the formation of Russian statehood to modernity. 2. The service strategy for any specialist activity is determined. It is argued that the ethics of every profession can be built around the idea of service. 3. The direction of the formation of students’ attitudes towards an acquired profession based on service is proposed. They are: awareness of the importance of labor; assessment of the work role as a goal; developed social responsibility; acceptance of service as one of life’s principles. 4. Meaningful guidelines are outlined in the discussion of possible difficulties, that may arise on the path of professional service. Such changes include: loss of motivation; loss of professionalism value; refusal of a lifelong professional trajectory. The research is exploratory in nature, but the results obtained turn out to be fruitful for the exchange of the first experience of conducting the course “Fundamentals of Russian Statehood”, and later, theoretical and methodological discussion with possible correction of educational material.